Description

Pazufloxacin is a synthetic fluoroquinolone antibiotic known for its potent antibacterial activity against a broad spectrum of Gram-positive and Gram-negative pathogens. Its primary value lies in its efficacy against multi-drug resistant bacterial strains, making it a critical component in advanced therapeutic formulations. This compound is essential for pharmaceutical manufacturers and research institutions developing next-generation antibacterial agents, particularly for ophthalmic and injectable solutions.

Application

• Pharmaceutical Active Ingredient (API): Core component in the synthesis of antibacterial medications.
• Ophthalmic Solutions: Used in the formulation of eye drops and ointments for treating bacterial conjunctivitis and corneal ulcers.
• Injectable Formulations: Serves as the active pharmaceutical ingredient in intravenous and intramuscular antibiotic preparations.
• Veterinary Medicine: Employed in developing antibacterial treatments for livestock and companion animals.
• Research & Development: A key reference standard and intermediate in microbiological and pharmacological research for studying quinolone resistance mechanisms.
• Combination Therapies: Used in synergistic drug combinations to enhance efficacy and combat resistance.

Basic Information

Product Name	Pazufloxacin
CAS No.	127045-41-4
Molecular Formula	C16H15FN2O4
Molecular Weight	318.30 g/mol
Synonyms	Pazufloxacin; Pazufloxacin Mesilate (salt form); (+-)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; T-3761; T-3762; Pasil; Pazucross; (RS)-Pazufloxacin
EINECS	Contact for details

Quality Control

Our Pazufloxacin is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and stringent control of related substances and residual solvents. Certificates of Analysis (COA) compliant with cGMP guidelines are provided with every shipment to guarantee traceability and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/JP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.