Description

Pazufloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic. This compound is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including strains resistant to other agents. It is primarily utilized in the pharmaceutical industry for the research and development of advanced antibacterial treatments. Pazufloxacin CAS NO 127045-37-8 represents a critical intermediate and active pharmaceutical ingredient for addressing complex infections.

Application

• Pharmaceutical API Synthesis: Serves as a key active pharmaceutical ingredient (API) in the formulation of injectable antibacterial drugs.
• Veterinary Medicine: Used in the development of antibacterial treatments for livestock and companion animals.
• Clinical Research: Employed as a reference standard in microbiological assays and pharmacokinetic studies.
• Antibacterial Agent Development: Acts as a lead compound for synthesizing novel fluoroquinolone derivatives with improved efficacy.
• Hospital-Acquired Infection Treatment: Investigated for use in combating multidrug-resistant infections in clinical settings.

Basic Information

Product Name	Pazufloxacin
CAS No.	127045-37-8
Molecular Formula	C16H15FN2O4
Molecular Weight	318.30 g/mol
Synonyms	Pazufloxacin; Pazufloxacin Mesilate (salt form); (+-)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; T-3761; T-3762; (+-)-9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperazinyl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic Acid; AM-833
EINECS	Contact for details

Quality Control

Our Pazufloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Microbial Limits	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.