Description

iso-Atrial Natriuretic Peptide (23-39) is a synthetic peptide fragment corresponding to a specific region of the atrial natriuretic peptide (ANP) hormone. This compound is a critical research tool for investigating the structure-activity relationships, receptor binding mechanisms, and metabolic pathways of the natriuretic peptide system. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on cardiovascular physiology, hypertension research, and novel therapeutic discovery.

Application

• Biochemical Research: Used as a reference standard and competitive ligand in receptor binding assays to study ANP receptor subtypes (NPR-A, NPR-C).
• Cardiovascular Pharmacology: Serves as a key intermediate or analytical standard in the development and screening of natriuretic peptide-based therapeutics.
• Metabolic Studies: Employed to investigate the enzymatic degradation pathways of ANP and the role of specific peptide fragments.
• Antibody Production: Acts as an antigen for generating specific antibodies used in immunoassays (ELISA, RIA) for ANP detection and quantification.
• Signal Transduction Research: Utilized to probe the downstream cellular signaling events mediated by natriuretic peptide receptors.
• Quality Control: Functions as a system suitability standard in analytical methods (HPLC, MS) for related peptide pharmaceuticals.

Basic Information

Product Name	iso-Atrial Natriuretic Peptide (23-39)
CAS No.	126889-20-1
Molecular Formula	C73H122N24O22
Molecular Weight	1639.9 g/mol
Synonyms	ANP (23-39); Atriopeptin (23-39); iso-ANP (23-39); Cardionatrin (23-39); Atrial Natriuretic Factor Fragment (23-39); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-OH; SR 163-39
EINECS	Contact for details

Quality Control

Our iso-Atrial Natriuretic Peptide (23-39) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including reversed-phase HPLC for purity assessment and mass spectrometry (MS) for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.