Description

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a critical protein target for pharmaceutical research and development, specifically associated with the treatment of cystic fibrosis. This high-purity biochemical is essential for advanced research, drug discovery, and the development of targeted therapies. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and academic laboratories focused on respiratory diseases and ion channel modulation.

Application

• Pharmaceutical Reference Standard: Serves as a critical benchmark for the development and quality control of CFTR modulator drugs.
• Drug Discovery & Screening: Used in high-throughput screening (HTS) assays to identify and validate novel therapeutic compounds targeting the CFTR protein.
• Biochemical Research: Fundamental for in-vitro studies investigating CFTR protein function, structure, and interaction mechanisms.
• Diagnostic Development: Employed in the development of diagnostic kits and assays for cystic fibrosis-related research.
• Academic & Clinical Research: Supports basic science and translational research in pulmonary medicine and genetic disorders.

Basic Information

Product Name	Cystic Fibrosis Transmembrane Conductance Regulator
CAS No.	126880-72-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CFTR; Cystic Fibrosis Transmembrane Conductance Regulator (ATP-binding cassette sub-family C, member 7); ABCC7; cAMP-dependent chloride channel; MRP7; TNR-CFTR; CFTR/MRP
EINECS	Contact for details

Quality Control

Our Cystic Fibrosis Transmembrane Conductance Regulator is produced under stringent conditions to ensure the highest standards of purity and biological activity, suitable for research and development applications. Each batch is supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and activity are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to prevent degradation. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Assessed by functional assay
Endotoxin Level	< 1.0 EU/mg
Water Content (KF)	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.