Description

Benzenethiol, 2-Amino-4,6-Difluoro- (9Ci) is a specialized aromatic thiol derivative featuring amino and fluoro substituents, offering a unique combination of nucleophilicity and electronic properties. This compound is a high-value intermediate prized for its role in constructing complex heterocyclic scaffolds and facilitating selective chemical transformations. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its fluorine-containing structure for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Utilized to develop activity-based probes and labeling reagents for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functional group manipulation.

Basic Information

Item	Details
Product Name	Benzenethiol, 2-Amino-4,6-Difluoro- (9Ci)
CAS No.	126764-60-1
Molecular Formula	C6H5F2NS
Molecular Weight	161.17 g/mol
Synonyms	2-Amino-4,6-difluorobenzenethiol; 4,6-Difluoro-2-aminobenzenethiol; 2-Amino-4,6-difluorothiophenol; 2-Amino-4,6-difluorophenyl mercaptan; 126764-60-1; AI3-32400; SCHEMBL218040; ZINC000005043761
EINECS	Contact for details

Quality Control

Every batch of Benzenethiol, 2-Amino-4,6-Difluoro- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This product is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.