Description

Chromogranin A (1-76) CAS NO 126729-24-6 is a defined peptide fragment derived from the larger chromogranin A protein, a key marker for neuroendocrine cells. This high-purity reference standard is critical for research and diagnostic assay development, ensuring accurate quantification and characterization. It is primarily utilized by pharmaceutical R&D teams, clinical diagnostics manufacturers, and academic researchers focused on neuroendocrine tumor biomarkers and secretory granule biology.

Application

• Reference Standard for Immunoassays: Serves as a primary calibrator or quality control material in ELISA and RIA kits for Chromogranin A detection.
• Biomarker Research: Used in studies investigating neuroendocrine tumors (NETs), including carcinoid tumors and pheochromocytoma.
• Antibody Production & Validation: Essential for the development, purification, and specificity testing of monoclonal and polyclonal antibodies.
• Cell Biology Studies: Applied in research on secretory granule function and hormone co-secretion mechanisms.
• Diagnostic Kit Manufacturing: Incorporated into in-vitro diagnostic (IVD) devices for clinical testing.
• Pharmaceutical Development: Used in drug discovery programs targeting neuroendocrine pathways.

Basic Information

Product Name	Chromogranin A (1-76)
CAS No.	126729-24-6
Molecular Formula	C378H600N104O108S2
Molecular Weight	8484.8 g/mol
Synonyms	Chromogranin A Fragment 1-76; CgA (1-76); Chromogranin-A (1-76); Vasostatin-1; Human Chromogranin A Peptide (1-76); hCgA1-76; Chromogranin A N-terminal Fragment; Pancreastatin precursor fragment
EINECS	Contact for details

Quality Control

Our Chromogranin A (1-76) is manufactured under strict quality systems. Each batch is characterized using advanced analytical techniques including HPLC for purity and mass spectrometry for identity confirmation, ensuring it meets the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.