Description

Fmoc-Dl-Valine CAS NO 126727-02-4 is a protected amino acid derivative where the amine group is shielded by a 9-fluorenylmethoxycarbonyl (Fmoc) group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled, sequential assembly of complex peptides and proteins. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the automated or manual synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs, hormones, and vaccines.
• Bioconjugation: Serves as a precursor for creating peptide tags or linkers for protein labeling and immobilization.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening of bioactive peptide sequences.
• Academic Research: Essential for biochemical and structural biology studies investigating protein function and interactions.
• Production of Protected Peptide Fragments: For use in fragment condensation strategies to construct long or difficult peptide sequences.

Basic Information

Product Name	Fmoc-Dl-Valine
CAS No.	126727-02-4
Molecular Formula	C₂₁H₂₃NO₄
Molecular Weight	353.41 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-DL-valine; Fmoc-DL-Val-OH; Fmoc-DL-Val; DL-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-methylbutanoic acid; N-Fmoc-DL-valine; 9-Fluorenylmethyloxycarbonyl-DL-valine; (RS)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Dl-Valine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.