Description

Methyl-D-Phe-L-Pro-[(S)-4-Guanidino-1-Formylbutyl]Nh2·Sulfuric Acid CAS NO 126721-07-1 is a chemically synthesized, high-purity peptide derivative supplied as a sulfate salt. This compound serves as a critical building block and advanced intermediate in the research and development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in peptide-based drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Development: Serves as a core structural component in the design of enzyme inhibitors targeting specific proteases.
• Bioconjugation & Peptide Engineering: Employed in the modification and functionalization of peptide sequences for enhanced stability or targeting.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in GMP/GLP environments.
• Academic & Contract Research: Supports biochemical and pharmacological research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	Methyl-D-Phe-L-Pro-[(S)-4-Guanidino-1-Formylbutyl]Nh2·Sulfuric Acid
CAS No.	126721-07-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methyl-D-Phe-L-Pro-[(S)-4-Guanidino-1-Formylbutyl]amine sulfate; D-Phe-L-Pro-[(S)-4-Guanidino-1-Formylbutyl] methylamine sulfate; (S)-4-Guanidino-1-formylbutyl-D-Phe-L-Pro methylamide sulfate; Peptide derivative 126721-07-1; Guanidino-formylbutyl peptide intermediate; Argatroban related intermediate; Thrombin inhibitor intermediate; Methyl-D-phenylalanyl-L-prolyl-[(S)-4-guanidino-1-formylbutyl]amine sulfate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial needs with material suitable for GMP starting material applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.