Description

Fmoc-Acpc-Oh CAS NO 126705-22-4 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled and efficient construction of complex peptide sequences in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences industries for the production of therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block (Fmoc-amino acid) for the sequential assembly of custom peptide chains.
• Pharmaceutical R&D: Used in the discovery and development of novel therapeutic peptides targeting various diseases.
• Peptidomimetic Design: Incorporation of the 1-aminocyclopentane-1-carboxylic acid (Acpc) scaffold to create metabolically stable peptide analogs.
• Combinatorial Chemistry Libraries: A key reagent for generating diverse peptide libraries for high-throughput screening.
• Bioconjugation: The carboxylic acid group allows for further functionalization and conjugation to other molecules or surfaces.
• Academic Research: Employed in biochemical and biophysical studies to investigate protein structure-function relationships.

Basic Information

Product Name	Fmoc-Acpc-Oh
CAS No.	126705-22-4
Molecular Formula	C₂₁H₂₁NO₄
Molecular Weight	351.40 g/mol
Synonyms	Fmoc-1-Aminocyclopentane-1-carboxylic acid; Fmoc-Acpc-OH; N-(9-Fluorenylmethoxycarbonyl)-1-aminocyclopentane-1-carboxylic acid; 1-[(9H-Fluoren-9-ylmethoxy)carbonylamino]cyclopentane-1-carboxylic acid; Fmoc-ACPC-OH; N-Fmoc-1-amino-1-cyclopentanecarboxylic acid; Fmoc-cyclopentylglycine; N-α-Fmoc-1-aminocyclopentanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Acpc-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.