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Alanyl-Prolyl-Glycyl-Tryptophanamide CAS NO 126675-52-3


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CAS No.:126675-52-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Alanyl-Prolyl-Glycyl-Tryptophanamide is a synthetic tetrapeptide sequence of significant interest in biochemical research and pharmaceutical development. This compound is valued for its role as a model substrate and building block in peptide science, enabling the study of enzymatic activity, molecular interactions, and structure-activity relationships. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on proteomics, drug discovery, and advanced therapeutic peptide synthesis.

Application

  • Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the discovery and optimization of novel peptide-based therapeutics.
  • Biochemical Assay Development: Used as a substrate or inhibitor in enzymatic studies to investigate protease specificity and kinetics.
  • Proteomics and Molecular Biology: Employed in research exploring protein-protein interactions, signal transduction pathways, and cellular processes.
  • Peptide Synthesis: Acts as a key building block for the solid-phase or solution-phase synthesis of longer, more complex peptide chains.
  • Academic Research: Utilized in university laboratories for teaching and fundamental research in biochemistry, medicinal chemistry, and peptide science.
  • Quality Control & Analytical Standards: Functions as a high-purity reference material for method validation and calibration in analytical laboratories.

Basic Information

Product Name Alanyl-Prolyl-Glycyl-Tryptophanamide
CAS No. 126675-52-3
Molecular Formula C25H32N8O5
Molecular Weight 524.57 g/mol
Synonyms APGW-NH2; H-Ala-Pro-Gly-Trp-NH2; L-Alanyl-L-prolylglycyl-L-tryptophanamide; Tetrapeptide APGW; Ala-Pro-Gly-Trp-amide; APGW Amide; Growth Hormone Releasing Peptide Fragment
EINECS Contact for details

Quality Control

Our Alanyl-Prolyl-Glycyl-Tryptophanamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Single Impurity (HPLC) ≤ 2.0%
Peptide Content ≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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