Description

4(1H)-Pyrimidinone, 6-(Difluoromethyl)- (9Ci) is a specialized heterocyclic organic compound featuring a difluoromethyl substituent, which imparts unique electronic and steric properties. This compound is a valuable high-purity building block in advanced chemical synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for creating new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for antiviral, anticancer, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components for electronic materials.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	4(1H)-Pyrimidinone, 6-(Difluoromethyl)- (9Ci)
CAS No.	126538-89-4
Molecular Formula	C5H4F2N2O
Molecular Weight	146.10 g/mol
Synonyms	6-(Difluoromethyl)-4(1H)-pyrimidinone; 6-(Difluoromethyl)pyrimidin-4(1H)-one; 6-(Difluoromethyl)-1H-pyrimidin-4-one; 4-Hydroxy-6-(difluoromethyl)pyrimidine; 6-Difluoromethyl-4-pyrimidinol; 4-Pyrimidinol, 6-(difluoromethyl)-; 1H-Pyrimidin-4-one, 6-(difluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 4(1H)-Pyrimidinone, 6-(Difluoromethyl)- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.