Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl)Aniline is a high-value, multi-halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group, makes it an indispensable intermediate for creating compounds with tailored electronic and steric properties. This product is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including herbicides, insecticides, and pharmaceutical candidates.

Application

• Key synthetic intermediate in the research and development of novel pharmaceutical compounds, particularly those targeting central nervous system and metabolic diseases.
• Critical building block for the synthesis of advanced agrochemicals, including next-generation herbicides and insecticides with improved efficacy and environmental profiles.
• Precursor in the development of functional materials, such as liquid crystals and organic semiconductors, where its halogenated structure influences electronic properties.
• Used in organic synthesis for the introduction of the 2-fluoro-5-(trifluoromethyl)aniline moiety into more complex molecular architectures.
• Intermediate in the manufacture of dyes and pigments requiring specific halogen substitution for color fastness and stability.
• Starting material for the preparation of metal-organic frameworks (MOFs) and other coordination polymers with specialized adsorption properties.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl)Aniline
CAS No.	126538-85-0
Molecular Formula	C7H4ClF4N
Molecular Weight	213.56 g/mol
Synonyms	2-Fluoro-3-chloro-5-(trifluoromethyl)aniline; 3-Chloro-2-fluoro-5-(trifluoromethyl)benzenamine; Benzenamine, 3-chloro-2-fluoro-5-(trifluoromethyl)-; 5-Amino-2-chloro-6-fluorobenzotrifluoride; 2-Chloro-6-fluoro-α,α,α-trifluoro-p-toluidine; 3-Chloro-2-fluoro-α,α,α-trifluoro-p-toluidine; 3-Chloro-2-fluoro-5-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting purity (typically ≥97% by HPLC), residual solvents, and other critical parameters are available upon request. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames. Isolate from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.