Description

5-Chloro-4-Hydroxy-6-Trifluoromethyl-Pyrimidine is a high-value pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring chloro, hydroxy, and trifluoromethyl substituents, makes it an essential intermediate for creating compounds with tailored biological and physical properties. This product is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	5-Chloro-4-Hydroxy-6-Trifluoromethyl-Pyrimidine
CAS No.	126538-83-8
Molecular Formula	C5H2ClF3N2O
Molecular Weight	198.53 g/mol
Synonyms	4-Hydroxy-5-chloro-6-(trifluoromethyl)pyrimidine; 5-Chloro-6-(trifluoromethyl)-4-pyrimidinol; 4-Pyrimidinol, 5-chloro-6-(trifluoromethyl)-; 6-Trifluoromethyl-5-chloro-4-hydroxypyrimidine; 5-Chloro-4-hydroxy-6-trifluoromethylpyrimidine; 5-Chloro-6-trifluoromethyl-4-pyrimidinol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 5-Chloro-4-Hydroxy-6-Trifluoromethyl-Pyrimidine is analyzed using advanced techniques like HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support audits to ensure compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.