Description

4(1H)-Pyrimidinone, 2,3-Dihydro-5-Hydroxy-2-Thioxo- (9Ci) is a specialized heterocyclic building block with a unique thioxo and hydroxy substitution pattern. This compound matters as a critical intermediate for synthesizing novel pharmacologically active molecules, particularly in medicinal chemistry research. It is needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel antiviral, anticancer, and antimicrobial agents.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive scaffolds.
• Agrochemical Synthesis: Acts as a precursor for developing new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Organic Synthesis Building Block: Employed in complex organic synthesis for constructing fused heterocyclic systems due to its reactive functional groups.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	4(1H)-Pyrimidinone, 2,3-Dihydro-5-Hydroxy-2-Thioxo- (9Ci)
CAS No.	126365-49-9
Molecular Formula	C4H4N2O2S
Molecular Weight	144.15 g/mol
Synonyms	2-Thioxo-2,3-dihydro-5-hydroxypyrimidin-4(1H)-one; 5-Hydroxy-2-mercapto-4-pyrimidinone; 2,3-Dihydro-5-hydroxy-2-thioxo-4(1H)-pyrimidinone; 2-Mercapto-5-hydroxy-4-pyrimidinone; 5-Hydroxy-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 4-Pyrimidinol, 2,3-dihydro-2-thioxo-; 2-Thioxo-5-hydroxy-2,3-dihydro-4(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 4(1H)-Pyrimidinone, 2,3-Dihydro-5-Hydroxy-2-Thioxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure consistent quality and reliable performance in your synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.