Description

Pyrimidine, 2,4,6-Trimethoxy-5-(Trimethylsilyl)- (9Ci) is a high-value, functionalized pyrimidine derivative characterized by its unique silyl and methoxy substituents. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life sciences industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a protected or functionalized pyrimidine scaffold in medicinal chemistry.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	Pyrimidine, 2,4,6-Trimethoxy-5-(Trimethylsilyl)- (9Ci)
CAS No.	126327-72-8
Molecular Formula	C12H22N2O3Si
Molecular Weight	270.40 g/mol
Synonyms	5-(Trimethylsilyl)-2,4,6-trimethoxypyrimidine; 2,4,6-Trimethoxy-5-(trimethylsilyl)pyrimidine; 5-Trimethylsilyl-2,4,6-trimethoxypyrimidine; Pyrimidine, 5-(trimethylsilyl)-2,4,6-trimethoxy-; 126327-72-8; 2,4,6-Trimethoxy-5-trimethylsilylpyrimidine
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 2,4,6-Trimethoxy-5-(Trimethylsilyl)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere such as nitrogen or argon after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.