Description

2,3,5,6-Tetrafluorophenyl-5-Iodo-4-Pentenoate is a specialized fluorinated and iodinated organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both perfluorinated aromatic and vinyl iodide functional groups, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorine and iodine atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with unique electronic or surface properties.
• Cross-Coupling Reactions: The vinyl iodide moiety is highly reactive in palladium-catalyzed reactions like Heck, Sonogashira, and Suzuki couplings for carbon-carbon bond formation.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the synthesis and reactivity of perfluorinated aromatics.
• Ligand and Catalyst Development: Can be used to synthesize complex chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2,3,5,6-Tetrafluorophenyl-5-Iodo-4-Pentenoate
CAS No.	126296-29-5
Molecular Formula	C11H5F4IO2
Molecular Weight	372.06 g/mol
Synonyms	5-Iodo-4-penten-1-oic Acid 2,3,5,6-Tetrafluorophenyl Ester; 4-Pentenoic Acid, 5-Iodo-, 2,3,5,6-Tetrafluorophenyl Ester; Tetrafluorophenyl 5-Iodopent-4-Enoate; 2,3,5,6-Tetrafluorophenyl 5-Iodo-4-Pentenoate; Pentafluorophenyl Iodopentenoate (related); Vinyl Iodide Tetrafluorophenyl Ester; Fluorinated Aryl Vinyl Iodide Ester
EINECS	Contact for details

Quality Control

Our production of 2,3,5,6-Tetrafluorophenyl-5-Iodo-4-Pentenoate adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.