Description

4-Ethoxy-2,3-Difluorophenol is a versatile fluorinated phenolic compound characterized by its ethoxy and difluoro substituents. This structural motif makes it a valuable advanced pharmaceutical intermediate and a key building block in the synthesis of complex organic molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorophenol moiety enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic display applications.
• Polymer Science: Acts as a monomer or modifier in the synthesis of specialty polymers and resins with unique thermal or chemical resistance properties.
• Organic Synthesis: A versatile reagent for introducing the 2,3-difluoro-4-ethoxyphenyl group into more complex molecular architectures in medicinal and materials chemistry.
• Chemical Research: Employed in academic and industrial R&D settings for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	4-Ethoxy-2,3-Difluorophenol
CAS No.	126163-56-2
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	2,3-Difluoro-4-ethoxyphenol; 4-Ethoxy-2,3-difluorophenol; 1-Ethoxy-2,3-difluoro-4-hydroxybenzene; Phenol, 4-ethoxy-2,3-difluoro-; 2,3-Difluoro-4-hydroxyanisole
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2,3-Difluorophenol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.