Description

Cyclopropanecarboxylicacid,1-Amino-,Hydrate(2:1)(9Ci) is a specialized amino acid derivative featuring the strained cyclopropane ring system. This compound is valued for its unique structural motif, which is of significant interest in advanced organic synthesis and pharmaceutical research. It serves as a critical chiral building block for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and complex organic molecules. The product is supplied as a hydrate to ensure stability and is identified by CAS No. 126115-44-4.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the cyclopropane ring can impart specific biological activity and stability.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into peptide backbones to create conformationally restricted analogs for studying protein-protein interactions.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new ring-opening and functionalization reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various high-tech industries.

Basic Information

Product Name	Cyclopropanecarboxylicacid,1-Amino-,Hydrate(2:1)(9Ci)
CAS No.	126115-44-4
Molecular Formula	C4H7NO2 · 1/2H2O
Molecular Weight	108.10 g/mol (Anhydrous basis)
Synonyms	1-Aminocyclopropanecarboxylic acid hydrate; 1-Amino-1-cyclopropanecarboxylic acid hemihydrate; ACC hydrate; (1-Aminocyclopropyl)carboxylic acid hydrate; NSC 163022 (hydrate); Cyclopropane-1-carboxylic acid, 1-amino-, hydrate (2:1); 1-Aminocyclopropane-1-carboxylic acid hemihydrate; ACPC hydrate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylicacid,1-Amino-,Hydrate(2:1)(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the original container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect purity and stability. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	Theoretical (Hemihydrate)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.