Description

3'-Trifluoromethylbiphenyl-3-Carbaldehyde is a high-purity, specialty aromatic aldehyde building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive aldehyde group and a trifluoromethyl-substituted biphenyl scaffold, enabling the introduction of lipophilic and electron-withdrawing motifs into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology, where the trifluoromethyl group can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides, leveraging the biphenyl structure for target binding and the CF3 group for improved environmental persistence and efficacy.
• Ligand and Catalyst Development: Serves as a starting material for constructing sophisticated chiral ligands, organocatalysts, and metal-organic frameworks (MOFs) used in asymmetric synthesis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers where the conjugated biphenyl system and fluorine atoms tune electronic properties and material stability.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags, photoaffinity labels, and other molecular probes to study biological processes and protein interactions.

Basic Information

Product Name	3'-Trifluoromethylbiphenyl-3-Carbaldehyde
CAS No.	126091-24-5
Molecular Formula	C14H9F3O
Molecular Weight	250.22 g/mol
Synonyms	[3-(3-Trifluoromethylphenyl)phenyl]methanal; 3'-Trifluoromethyl-[1,1'-biphenyl]-3-carboxaldehyde; 3-Formyl-3'-trifluoromethylbiphenyl; 3-(3-Trifluoromethylphenyl)benzaldehyde; 3'-Trifluoromethylbiphenyl-3-aldehyde; Biphenyl-3-carbaldehyde, 3'-trifluoromethyl-; 3-Carbaldehyde-3'-trifluoromethylbiphenyl
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethylbiphenyl-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.