Description

Succinimidyl n-(N'-(3-Azido-5-Nitrobenzoyl)Tyrosyl)-β-Alanate CAS NO 126083-10-1 is a specialized heterobifunctional crosslinking reagent designed for advanced bioconjugation and proteomics research. This compound is engineered to facilitate the site-specific labeling of biomolecules, offering researchers a powerful tool for creating stable, well-defined conjugates. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical development, diagnostics, and life sciences research.

Application

• Bioconjugation and Protein Labeling: For the covalent attachment of probes, drugs, or other molecules to proteins, antibodies, and peptides.
• Proteomics Research: Used in the development of affinity tags, activity-based probes, and for studying protein-protein interactions.
• Antibody-Drug Conjugate (ADC) Development: Serves as a critical linker component for attaching cytotoxic payloads to monoclonal antibodies.
• Diagnostic Assay Development: Enables the creation of labeled antigens or antibodies for ELISA, lateral flow assays, and other immunoassays.
• Surface Functionalization: For modifying nanoparticles, biosensors, and microarray surfaces with biomolecules for enhanced detection and specificity.
• Materials Science: Incorporation into polymers or hydrogels to create bioactive materials for tissue engineering and drug delivery systems.

Basic Information

Product Name	Succinimidyl n-(N'-(3-Azido-5-Nitrobenzoyl)Tyrosyl)-β-Alanate
CAS No.	126083-10-1
Molecular Formula	C25H23N7O9
Molecular Weight	565.49 g/mol
Synonyms	N-Succinimidyl 3-((2-(3-azido-5-nitrobenzamido)-3-(4-hydroxyphenyl)propanamido)propanoate; 3-Azido-5-nitro-N-[(2S)-1-[[3-[(2,5-dioxopyrrolidin-1-yl)oxy]-3-oxopropyl]amino]-1-oxo-3-(4-hydroxyphenyl)propan-2-yl]benzamide; N-(3-Azido-5-nitrobenzoyl)-L-tyrosyl-β-alanine N-hydroxysuccinimide ester; Heterobifunctional Crosslinker (NHS ester/Azide); NHS-PEG4-Azide (structural analog); Tyrosine-based Click Chemistry Reagent; Azido-NHS Ester Crosslinker
EINECS	Contact for details

Quality Control

Our Succinimidyl n-(N'-(3-Azido-5-Nitrobenzoyl)Tyrosyl)-β-Alanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and performance for sensitive research applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.