Description

H-Gly-Pro-Arg-Pro-NH2 is a synthetic peptide sequence with the CAS registry number 126047-75-4. This compound is a valuable biochemical tool and intermediate, particularly noted for its role in modulating enzymatic activity and studying protein-protein interactions. It is primarily utilized by research institutions and pharmaceutical developers engaged in proteomics, drug discovery, and biochemical assay development. The peptide's specific sequence offers targeted functionality for advanced life science applications.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for proteases like thrombin and other serine proteases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery and development of novel therapeutic agents targeting coagulation pathways.
• Proteomics & Diagnostics: Employed in assay development for diagnostic kits and research tools to study blood coagulation disorders and related biological processes.
• Life Science Reagents: Incorporated into high-purity reagent kits for academic, clinical, and industrial laboratories.
• Peptide Synthesis: Acts as a building block for the solid-phase or solution-phase synthesis of longer, more complex peptide chains.

Basic Information

Product Name	H-Gly-Pro-Arg-Pro-NH2
CAS No.	126047-75-4
Molecular Formula	C20H35N9O5
Molecular Weight	481.55 g/mol
Synonyms	Gly-Pro-Arg-Pro-NH2; GPRP-NH2; Thrombin Inhibitor Peptide (GPRP); H-Glycyl-L-prolyl-L-arginyl-L-prolinamide; GPRP amide; L-Glycyl-L-prolyl-L-arginyl-L-prolinamide; Benzamidine derivative peptide; Protease inhibitor sequence GPRP
EINECS	Contact for details

Quality Control

Our H-Gly-Pro-Arg-Pro-NH2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity checks, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -15°C to -25°C (freezer) for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For extended storage under inert atmosphere, contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.