Description

4-Chloro-6-Methyl-2-[4-(Trifluoromethyl)Phenyl]Pyrimidine is a high-value pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This product is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Chemical Research (R&D): A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial laboratories.
• Fluorinated Compound Library: Integral for constructing libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	4-Chloro-6-Methyl-2-[4-(Trifluoromethyl)Phenyl]Pyrimidine
CAS No.	125904-05-4
Molecular Formula	C12H8ClF3N2
Molecular Weight	272.65 g/mol
Synonyms	2-(4-(Trifluoromethyl)phenyl)-4-chloro-6-methylpyrimidine; 4-Chloro-2-[4-(trifluoromethyl)phenyl]-6-methylpyrimidine; 4-Chloro-6-methyl-2-(4-trifluoromethylphenyl)pyrimidine; 4-Chloro-6-methyl-2-(α,α,α-trifluoro-p-tolyl)pyrimidine; 2-(4-Trifluoromethylphenyl)-4-chloro-6-methylpyrimidine; 4-Chloro-6-methyl-2-(4-trifluoromethylphenyl)-pyrimidine; 125904-05-4
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Methyl-2-[4-(Trifluoromethyl)Phenyl]Pyrimidine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.