Description

2-[3-(Trifluoromethyl)Phenyl]Ethanimidamide Hydrochloride is a high-purity, non-nucleoside organic building block featuring a trifluoromethylphenyl core. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and pesticides, leveraging the biological activity imparted by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals where the phenyl-ethanimidamide structure contributes to specific material properties.
• Chemical Biology & Proteomics: Employed as a building block for designing enzyme inhibitors, probes, and other bioactive tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on scale.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Phenyl]Ethanimidamide Hydrochloride
CAS No.	125903-76-6
Molecular Formula	C9H8F3N2·HCl
Molecular Weight	234.63 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenyl]acetamidine hydrochloride; 3'-(Trifluoromethyl)acetophenone amidine hydrochloride; α-(3-Trifluoromethylphenyl)acetamidine hydrochloride; N'-(3-Trifluoromethylbenzyl)acetamidine hydrochloride; 1-(3-Trifluoromethylphenyl)ethanimidamide hydrochloride; Amidrine derivative CAS 125903-76-6; TFMPA-HCl (abbrev.)
EINECS	Contact for details

Quality Control

Our 2-[3-(Trifluoromethyl)Phenyl]Ethanimidamide Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.