Description

Melanin-Concentrating Hormone Precursors CAS NO 125805-24-5 are specialized biochemical intermediates essential for research and development in neuroendocrinology and metabolic studies. These high-purity precursors are critical for investigating the synthesis and function of Melanin-Concentrating Hormone (MCH), a key neuropeptide involved in regulating energy homeostasis, feeding behavior, and sleep. They are primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for obesity, metabolic disorders, and central nervous system conditions.

Application

• Pharmaceutical Research & Development: Serving as key starting materials (KSMs) or advanced intermediates in the synthesis of Melanin-Concentrating Hormone (MCH) and its analogs for preclinical studies.
• Neuroendocrine Pathway Investigation: Used in biochemical assays to study the biosynthesis, regulation, and signaling pathways of MCH within the hypothalamus and other brain regions.
• Metabolic Disorder Research: Essential for creating tools and probes to explore the role of MCH in appetite control, energy balance, and the pathophysiology of obesity and diabetes.
• Peptide Chemistry & Synthesis: Valuable building blocks for solid-phase or solution-phase peptide synthesis, enabling the creation of modified MCH peptides with enhanced stability or activity.
• Academic & Institutional Studies: Supplied to universities and research institutes for fundamental research in neuroscience, endocrinology, and peptide biology.
• Biomarker Development: Potential use in developing diagnostic assays or imaging agents targeting the MCH system.

Basic Information

Product Name	Melanin-Concentrating Hormone Precursors
CAS No.	125805-24-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MCH Precursors; Pro-Melanin Concentrating Hormone fragments; Melanin-Concentrating Hormone prohormone intermediates; Neuropeptide MCH precursors; Hypothalamic peptide precursors; MCH (1-?) precursor analogs; Energy homeostasis peptide intermediates
EINECS	Contact for details

Quality Control

Our Melanin-Concentrating Hormone Precursors are manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation by mass spectrometry. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory and compliance needs in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.