Description

tert-Butyloxycarbonyl-Prolyl-Dehydrophenylalanyl-Glycyl-Ethylamide is a specialized protected peptide building block used in advanced organic synthesis. This compound is critical for the controlled assembly of complex peptide sequences, particularly those requiring the incorporation of a dehydroamino acid residue. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides and peptidomimetics. The product offers high purity and reliable performance for demanding synthetic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled, sequential construction of peptide chains on resin supports.
• Solution-Phase Peptide Synthesis: For the synthesis of specific peptide fragments in solution, often for convergent strategies.
• Peptidomimetic Research: Serving as a precursor for creating non-natural peptide analogs with enhanced stability or biological activity.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of peptide-based drug candidates, particularly those targeting specific enzymes or receptors.
• Bioconjugation: Potential use in the site-specific modification of peptides or proteins for labeling or functionalization.
• Academic Research: A valuable tool for studying peptide structure-activity relationships and synthetic methodology development.

Basic Information

Product Name	tert-Butyloxycarbonyl-Prolyl-Dehydrophenylalanyl-Glycyl-Ethylamide
CAS No.	125768-11-8
Molecular Formula	C25H34N4O6
Molecular Weight	486.56 g/mol
Synonyms	Boc-Pro-δPhe-Gly-NHEt; Boc-L-Prolyl-dehydro-L-phenylalanyl-glycyl ethylamide; N-(tert-Butoxycarbonyl)-L-prolyl-(Z)-dehydro-L-phenylalanyl-glycine ethylamide; Boc-Pro-δPhe-Gly-Et; tert-Butyl (S)-1-((S)-2-((2-ethoxy-2-oxoethyl)amino)-1-carboxy-2-phenylethenyl)pyrrolidine-2-carboxylate; Protected Tetrapeptide Building Block; Boc-Protected Dehydrophenylalanine Peptide
EINECS	Contact for details

Quality Control

Our tert-Butyloxycarbonyl-Prolyl-Dehydrophenylalanyl-Glycyl-Ethylamide is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research and development applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and related substance profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.