Description

Fmoc-L-Ser[α-(Gal-Beta(1-3)-Galnac)]-Oh Peracetate is a sophisticated, fully protected glycoamino acid building block, specifically designed for solid-phase peptide synthesis (SPPS). This compound is critical for the precise and efficient chemical synthesis of glycopeptides, which are essential for studying protein-glycan interactions and developing novel biotherapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced glycobiology, glycoengineering, and the development of peptide-based vaccines and diagnostics.

Application

• Glycopeptide Synthesis: A key protected intermediate for the automated solid-phase synthesis of O-linked glycopeptides.
• Glycobiology Research: Used in academic and industrial labs to study the structure, function, and biosynthesis of glycoproteins.
• Pharmaceutical Development: Serves as a building block for creating therapeutic glycopeptides, including potential anti-cancer and anti-inflammatory agents.
• Vaccine Development: Employed in the synthesis of glycoconjugate vaccine candidates that target specific carbohydrate antigens.
• Diagnostic Reagent Production: Used to create standardized glycopeptide antigens or probes for immunoassays and diagnostic kits.
• Chemical Biology Tool Development: Integral for creating activity-based probes or labeled glycopeptides to study enzymatic activity and cellular processes.

Basic Information

Product Name	Fmoc-L-Ser[α-(Gal-Beta(1-3)-Galnac)]-Oh Peracetate
CAS No.	125760-30-7
Molecular Formula	C48H56N2O20
Molecular Weight	981.0 g/mol (approx.)
Synonyms	Fmoc-Ser(Galβ1-3GalNAcα)-OH (peracetate); Fmoc-L-Serine, O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-, 9H-fluoren-9-ylmethyl ester, acetate (ester); Fmoc-Thomsen-Friedenreich (TF) antigen Serine derivative; Fmoc-Ser(TF antigen)-OH peracetate; Fmoc-O-(3-O-β-D-Galactopyranosyl-2-acetamido-2-deoxy-α-D-galactopyranosyl)-L-serine peracetate; Glycosylated Fmoc-Serine building block; Fmoc-Ser(Galβ1-3αGalNAc)-OH (Ac)4
EINECS	Contact for details

Quality Control

Every batch of Fmoc-L-Ser[α-(Gal-Beta(1-3)-Galnac)]-Oh Peracetate is produced and analyzed under strict quality management protocols to ensure the high purity and consistency required for sensitive research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.