Description

n-(9-Fluorenylmethoxycarbonyl)-L-Serine Phenacyl Ester is a specialized, protected amino acid derivative used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for complex molecular assembly. It is primarily utilized in the pharmaceutical and biotechnology sectors for the solid-phase synthesis of peptides and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected serine derivative for the sequential construction of peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation Chemistry: Acts as a precursor for creating modified peptides with specific functional handles for labeling or cross-linking.
• Combinatorial Chemistry Libraries: A valuable building block for generating diverse compound libraries for high-throughput screening in drug discovery.
• Academic & Industrial Research: Employed in laboratories for studying peptide structure, function, and for developing new synthetic methodologies.
• Production of Specialty Peptides: Used in the manufacture of custom peptides for diagnostic, research, and therapeutic applications.

Basic Information

Product Name	n-(9-Fluorenylmethoxycarbonyl)-L-Serine Phenacyl Ester
CAS No.	125760-26-1
Molecular Formula	C26H23NO6
Molecular Weight	445.47 g/mol
Synonyms	Fmoc-Ser(OPac)-OH; Fmoc-L-Serine phenacyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine 2-oxo-2-phenylethyl ester; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-hydroxypropanoic acid phenacyl ester; Fmoc-Ser-OPac; L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2-oxo-2-phenylethyl ester; Fmoc-Serine(Pac)-OH; N-Fmoc-O-phenacyl-L-serine
EINECS	Contact for details

Quality Control

Our n-(9-Fluorenylmethoxycarbonyl)-L-Serine Phenacyl Ester is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.