Description

Complement 3A(Tyr-70-77) is a defined synthetic peptide fragment derived from the Complement 3A protein. This high-purity reference standard is critical for research and development in immunology and biochemistry, providing a precise tool for studying complement system activation and protein-protein interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on inflammatory and autoimmune disease pathways.

Application

• Biochemical Research: Used as a reference standard in studies of the complement cascade, specifically for investigating the structure and function of the C3a anaphylatoxin fragment.
• Immunoassay Development: Serves as a critical antigen for the development and calibration of ELISA and other immunoassays targeting C3a or related peptides.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential drug candidates that modulate complement system activity.
• Antibody Production: Acts as an immunogen for generating specific polyclonal or monoclonal antibodies against the C3a(Tyr-70-77) epitope.
• Mass Spectrometry Standard: Provides a known mass for calibration and method development in proteomic analysis using LC-MS/MS techniques.
• Cell Signaling Studies: Applied in vitro to investigate cellular responses and receptor binding activities associated with the C3a fragment in immune cells.

Basic Information

Product Name	Complement 3A(Tyr-70-77)
CAS No.	125753-03-9
Molecular Formula	C44H62N12O13S
Molecular Weight	975.1 g/mol
Synonyms	C3a (70-77) (human); Complement C3a (Tyr70-Ser77); H-Tyr-Ser-Lys-Tyr-Phe-Ser-Arg-Trp-OH; C3a Anaphylatoxin (70-77); Complement Component 3a (70-77); C3a Peptide Fragment (70-77); Tyr-Ser-Lys-Tyr-Phe-Ser-Arg-Trp
EINECS	Contact for details

Quality Control

Our Complement 3A(Tyr-70-77) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	± 10% of theoretical
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.