Description

Myristoyl-Lys-Arg-Thr-Leu-Arg-Oh is a synthetic, myristoylated hexapeptide with the sequence Lys-Arg-Thr-Leu-Arg. This modification enhances its lipophilicity and membrane permeability, making it a valuable tool for biochemical research and development. It is particularly relevant for scientists investigating cell-penetrating peptides (CPPs), signal transduction pathways, and targeted drug delivery systems. This high-purity compound is essential for advanced studies in pharmacology, proteomics, and bioconjugation.

Application

• Biochemical Research: Used as a model cell-penetrating peptide (CPP) to study intracellular delivery mechanisms and membrane interactions.
• Pharmaceutical Development: Serves as a potential carrier moiety in the design of peptide-drug conjugates for enhanced cellular uptake of therapeutic agents.
• Signal Transduction Studies: Applied in research to investigate the role of protein lipidation (myristoylation) in cellular localization and signaling events.
• Proteomics & Peptide Synthesis: Acts as a key intermediate or reference standard in solid-phase peptide synthesis (SPPS) and analytical method development.
• Cosmeceutical Research: Explored for its potential in topical formulations aimed at enhancing the skin penetration of active ingredients.

Basic Information

Product Name	Myristoyl-Lys-Arg-Thr-Leu-Arg-Oh
CAS No.	125678-68-4
Molecular Formula	C41H78N14O9
Molecular Weight	887.15 g/mol
Synonyms	Myristoyl-KRTLR-OH; N-Myristoyl-L-lysyl-L-arginyl-L-threonyl-L-leucyl-L-arginine; Myr-Lys-Arg-Thr-Leu-Arg; CPP Myristoylated Hexapeptide; Myr-KRTLR; Nα-Myristoyl-Lys-Arg-Thr-Leu-Arg; Lipopeptide KRTLR
EINECS	Contact for details

Quality Control

Every batch of Myristoyl-Lys-Arg-Thr-Leu-Arg-Oh is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure sequence integrity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.