Description

Oxytocin, Mpa(1)-Cyclo(Glu(4)-Lys(8))- CAS NO 125666-62-8 is a synthetic, cyclic analog of the neuropeptide hormone oxytocin, designed for enhanced stability and receptor selectivity. This high-purity peptide is critical for advanced biochemical and pharmacological research, offering a reliable tool for studying oxytocin receptor-mediated pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroendocrinology, behavioral studies, and therapeutic development.

Application

• Neuroscientific Research: A key reagent for investigating the role of oxytocin in social behavior, bonding, stress response, and memory.
• Pharmacology & Drug Discovery: Used as a reference standard and lead compound in the development of novel therapeutics targeting the oxytocin receptor for conditions like autism, anxiety, and postpartum depression.
• Biochemical Assay Development: Serves as a critical component in establishing high-throughput screening (HTS) assays and receptor binding studies.
• Endocrinology Studies: Employed in vitro and in vivo to study uterine contraction mechanisms and lactation physiology.
• Stability & Structure-Activity Relationship (SAR) Studies: The cyclic structure makes it an ideal model for studying peptide stability and optimizing peptide-based drug candidates.

Basic Information

Product Name	Oxytocin, Mpa(1)-Cyclo(Glu(4)-Lys(8))- CAS NO 125666-62-8
CAS No.	125666-62-8
Molecular Formula	C45H68N12O12S2
Molecular Weight	1009.2 g/mol
Synonyms	1-Mercaptopropanoic Acid-1-cyclo(Glu(4)-Lys(8))-Oxytocin; [Mpa1, Lys8]-Oxytocin cyclic (4→8) lactam; Cyclo(4-8)[Mpa1, Lys8]oxytocin; Oxytocin cyclic lactam analog; Tocinoic acid cyclic analog; OT cyclic analog; Oxytocin (4-8) lactam derivative
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, purity by HPLC, and related substances. Our quality system is designed to meet the exacting standards required for pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.