Description

(Leu31,Pro34)-Neuropeptide Y (Porcine) is a synthetic analog of the endogenous neuropeptide Y, specifically modified to act as a potent and selective antagonist for Y1 receptors. This high-purity peptide is critical for advanced research in neurobiology, endocrinology, and metabolic disorders. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies for receptor binding studies, signal transduction pathway analysis, and the development of novel therapeutic agents.

Application

• Neuroscience Research: Investigation of NPY Y1 receptor function, localization, and signaling in the central and peripheral nervous systems.
• Pharmacological Studies: Used as a standard reference antagonist in competitive binding assays and functional bioassays to characterize new drug candidates.
• Metabolic Disorder Research: Exploration of NPY's role in appetite regulation, energy homeostasis, obesity, and diabetes.
• Cardiovascular Research: Study of NPY-mediated effects on blood pressure, heart rate, and vascular tone.
• Biochemical Tool: Essential reagent for elucidating the physiological and pathophysiological roles of the NPY system.
• Drug Discovery & Development: A key molecular tool for screening and validating compounds targeting the Y1 receptor for therapeutic intervention.

Basic Information

Product Name	(Leu31,Pro34)-Neuropeptide Y (Porcine)
CAS No.	125580-28-1
Molecular Formula	C190H287N55O57S
Molecular Weight	4253.7 g/mol
Synonyms	[Leu31, Pro34] NPY (porcine); [Leu31,Pro34]-NPY; NPY (porcine) [Leu31,Pro34] analog; Neuropeptide Y (porcine) (Leu31,Pro34)-; Neuropeptide Y Y1 receptor antagonist (porcine); pNPY (Leu31,Pro34); Y1 receptor antagonist; [Leu31,Pro34]-Neuropeptide Y
EINECS	Contact for details

Quality Control

Our (Leu31,Pro34)-Neuropeptide Y (Porcine) is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%
Biological Activity	Confirmed by functional assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.