Description

2-Piperazin-1-Ylpyrimidine CAS NO 125523-53-7 is a versatile heterocyclic organic compound featuring a pyrimidine core substituted with a piperazine moiety. This structure makes it a valuable and highly functionalized pharmaceutical intermediate and building block for medicinal chemistry research. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry to create libraries of novel compounds for biological evaluation.
• Ligand Synthesis: Serves as a core structure for developing ligands in catalysis and for creating molecular probes in biochemical research.
• Agrochemical Research: Employed in the research and development of new pesticides and herbicides, leveraging its heterocyclic scaffold.
• Material Science: Potential use as a monomer or functional additive in the development of advanced polymers and specialty materials.

Basic Information

Product Name	2-Piperazin-1-Ylpyrimidine
CAS No.	125523-53-7
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	2-(Piperazin-1-yl)pyrimidine; 1-(Pyrimidin-2-yl)piperazine; 2-(1-Piperazinyl)pyrimidine; Piperazine, 1-(2-pyrimidinyl)-; 2-Piperazin-1-yl-pyrimidine; Pyrimidine, 2-(1-piperazinyl)-; 2-Piperazinylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-Piperazin-1-Ylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance as a research-grade chemical. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.