Description

Neuropeptide K (1-24) is a bioactive peptide fragment derived from the larger neuropeptide K precursor. This compound is significant for its role in neurological research, particularly in the study of tachykinin receptor interactions and signaling pathways. It is primarily utilized by research institutions and pharmaceutical developers focused on neuroscience, pain management, and neuroendocrine system investigations.

Application

• Neuroscience Research: Used as a standard or reagent in studies of tachykinin receptors (NK1, NK2, NK3) and their physiological roles.
• Pharmacological Assays: Employed in in vitro and in vivo models to investigate peptide-receptor binding and signal transduction mechanisms.
• Biochemical Standard: Serves as a reference material in analytical methods such as HPLC and mass spectrometry for peptide quantification and identification.
• Drug Discovery: A key tool for screening and developing novel therapeutics targeting neurokinin pathways for conditions like pain, inflammation, and mood disorders.
• Academic & Institutional Research: Fundamental research into the structure-activity relationships (SAR) of neuropeptides.

Basic Information

Product Name	Neuropeptide K (1-24)
CAS No.	125408-80-2
Molecular Formula	C₁₂₀H₁₉₈N₄₀O₃₃
Molecular Weight	~2710.1 g/mol
Synonyms	Neuropeptide K (NPK) fragment 1-24; NPK (1-24); Tachykinin precursor 1 fragment 72-95 (human); Neuropeptide K (human); Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 (sequence for NPK 1-24); H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2; NPK-24
EINECS	Contact for details

Quality Control

Our Neuropeptide K (1-24) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to GMP principles for peptide synthesis, and specifications are designed to meet the rigorous demands of pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.