Description

H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Arg-Arg-Pro-Lys-Leu-Lys-Oh is a synthetic peptide of significant interest in biochemical and pharmacological research. This compound, identified by CAS number 125357-12-2, is valued for its specific sequence and potential biological activity. It is primarily utilized by research institutions and pharmaceutical developers engaged in advanced peptide studies, drug discovery, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard or tool compound in studies of peptide structure-activity relationships (SAR).
• Drug Discovery: Serves as a lead compound or intermediate in the development of peptide-based pharmaceuticals targeting specific receptors.
• Neuroscience Research: Potential applications in studying neuropeptide pathways and signaling mechanisms.
• Cell Biology: Investigation of cellular uptake mechanisms and intracellular signaling processes mediated by cationic peptides.
• Antimicrobial Peptide (AMP) Research: Exploration of its properties within the context of developing new antimicrobial agents.
• Pharmaceutical Intermediates: Acts as a key building block for the synthesis of more complex peptide conjugates or drug candidates.

Basic Information

Product Name	H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Arg-Arg-Pro-Lys-Leu-Lys-Oh
CAS No.	125357-12-2
Molecular Formula	C86H147N35O18
Molecular Weight	~1875.30 g/mol
Synonyms	Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Arg-Arg-Pro-Lys-Leu-Lys; YGGFLRRrRrPKLK-NH2 (single-letter code); H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Arg-Arg-Pro-Lys-Leu-Lys-Amide; Arg8-D-Arg9 Dynorphin A (1-13) amide analog; Dynorphin A (1-13) [Arg7, D-Arg8] amide; [D-Arg8]-Dynorphin A (1-13) amide; κ-opioid receptor peptide ligand analog
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and tested under stringent quality management systems. Each batch of H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Arg-Arg-Pro-Lys-Leu-Lys-Oh undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, MS confirmation, and other relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.