Description

Boc-Lys(Z)(Isopropyl)-Oh is a protected amino acid derivative, specifically a lysine derivative with orthogonal protecting groups. This compound is a crucial building block in the synthesis of complex peptides and peptidomimetics, offering precise control over chemical reactivity during multi-step organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing novel therapeutic agents and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with specific side-chain protection.
• Solution-Phase Peptide Chemistry: Used in the synthesis of peptide fragments and complex natural products requiring selective deprotection strategies.
• Pharmaceutical Research & Development: Serves as a critical raw material in the discovery and development of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation and Labeling: The orthogonal protecting groups allow for the selective modification of the lysine side chain for attaching labels, tags, or other functional molecules.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Academic & Institutional Research: A valuable reagent for studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Boc-Lys(Z)(Isopropyl)-Oh
CAS No.	125323-99-1
Molecular Formula	C₂₀H₃₀N₂O₆
Molecular Weight	394.47 g/mol
Synonyms	Nα-Boc-Nε-Z-L-lysine; Boc-Lys(Z)-OH; (2S)-6-{[(Benzyloxy)carbonyl]amino}-2-{[(tert-butoxy)carbonyl]amino}hexanoic acid; N-α-(tert-Butoxycarbonyl)-N-ε-(benzyloxycarbonyl)-L-lysine; Boc-Lys(Bz)-OH; Boc-Lys(Z); N-Boc-N'-CBZ-L-lysine; tert-Butyl N-[(2S)-6-{[(benzyloxy)carbonyl]amino}-1-hydroxy-1-oxohexan-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our Boc-Lys(Z)(Isopropyl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.