Description

3-o-(2-Acetamido-2-Deoxygalactopyranosyl)-Acetyl-Threonyl-Alanyl-Alanine Methyl Ester is a complex synthetic glycopeptide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard for studying glycosylation patterns, enzyme-substrate interactions, and carbohydrate-protein recognition events. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic tools, and biochemical probes. The precise structure and purity of this molecule are paramount for ensuring reproducible and reliable experimental outcomes in high-value applications.

Application

• Glycobiology Research: As a key intermediate or reference standard for investigating glycosylation pathways, lectin binding, and carbohydrate-mediated biological signaling.
• Pharmaceutical R&D: Used in the synthesis and study of glycopeptide-based drug candidates, including potential antimicrobials, antivirals, and cancer therapeutics.
• Enzymology Studies: Serves as a specific substrate or inhibitor for glycosyltransferases, glycosidases, and other enzymes involved in carbohydrate metabolism.
• Diagnostic Development: Employed in the design and calibration of assays and biosensors that detect specific carbohydrate-protein interactions.
• Bioconjugation & Probe Synthesis: Acts as a starting material for creating fluorescently labeled or affinity-tagged glycoconjugates for cellular imaging and pull-down assays.
• Academic Research: Provides a well-defined compound for fundamental studies in organic chemistry, medicinal chemistry, and structural biology.

Basic Information

Product Name	3-o-(2-Acetamido-2-Deoxygalactopyranosyl)-Acetyl-Threonyl-Alanyl-Alanine Methyl Ester
CAS No.	125316-77-0
Molecular Formula	C23H38N4O12
Molecular Weight	562.57 g/mol
Synonyms	Ac-Thr-Ala-Ala-OMe (GalNAc); O-(2-Acetamido-2-deoxy-α-D-galactopyranosyl)-N-acetyl-L-threonyl-L-alanyl-L-alanine methyl ester; N-Acetyl-Thr(α-D-GalNAc)-Ala-Ala-OMe; Glycopeptide TAA Methyl Ester (GalNAc); Thr(α-GalNAc)-Ala-Ala Methyl Ester; 3-O-(2-Acetamido-2-deoxy-α-D-galactopyranosyl)-N-acetyl-L-threonyl-L-alanyl-L-alanine methyl ester; Tn Antigen Glycopeptide Derivative; Ac-T(α-D-GalNAc)AA-OMe
EINECS	Contact for details

Quality Control

Our production of this advanced glycopeptide adheres to stringent quality protocols to ensure batch-to-batch consistency and structural integrity. Each lot is characterized using advanced analytical techniques, including HPLC for purity assessment, NMR and Mass Spectrometry for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >95% by HPLC), and specific impurity profiles is provided with every shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, temperature-controlled environment. This compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.