Description

5-Bromo-6-Ethoxy-5,6-Dihydro-2',3'-Isopropylidine-β-Ribofuranosyluracil is a high-purity, advanced pharmaceutical intermediate characterized by its modified ribofuranosyluracil structure. This compound is critical for research and development in nucleoside chemistry, serving as a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analogues for antiviral and anticancer applications.
• Antiviral Drug Research: Used in the development of potential therapeutics targeting viral polymerases and replication mechanisms.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed in studies investigating nucleoside metabolism, enzyme inhibition, and nucleic acid interactions.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	5-Bromo-6-Ethoxy-5,6-Dihydro-2',3'-Isopropylidine-β-Ribofuranosyluracil
CAS No.	125310-70-5
Molecular Formula	C15H21BrN2O7
Molecular Weight	421.24 g/mol
Synonyms	5-Bromo-6-ethoxy-5,6-dihydro-2',3'-O-isopropylideneuridine; 2',3'-O-Isopropylidene-5-bromo-6-ethoxy-5,6-dihydrouridine; 5-Bromo-6-ethoxy-5,6-dihydro-2',3'-O-(1-methylethylidene)uridine; 5-Bromo-6-ethoxy-2',3'-O-isopropylidene-5,6-dihydrouridine; 5-Br-6-EtO-dh-2',3'-O-iPr-uridine; Modified Uridine Intermediate; Brominated Dihydrouridine Derivative
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Ethoxy-5,6-Dihydro-2',3'-Isopropylidine-β-Ribofuranosyluracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.