Description

Phthaloyl-Glycyl(P)-Isoleucyl-Tryptophyl-Benzylamide is a synthetic, protected peptide derivative with the CAS number 125009-80-5. This compound serves as a crucial advanced intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by pharmaceutical research organizations and fine chemical manufacturers engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block in the solid-phase and solution-phase synthesis of novel therapeutic peptides.
• Drug Discovery Research: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new bioactive compounds.
• Bioconjugation: Serves as a precursor for creating peptide-based probes, labels, or drug conjugates for diagnostic and therapeutic applications.
• Academic Research: Employed in university and institutional labs for studying peptide chemistry, folding, and receptor-ligand interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized peptides for clients.

Basic Information

Product Name	Phthaloyl-Glycyl(P)-Isoleucyl-Tryptophyl-Benzylamide
CAS No.	125009-80-5
Molecular Formula	C38H41N5O6
Molecular Weight	663.77 g/mol
Synonyms	Phth-Gly-Ile-Trp-NHBn; N-Phthaloylglycyl-L-isoleucyl-L-tryptophan benzylamide; Benzyl (2S)-2-[[(2S)-2-[[2-(1,3-dioxoisoindolin-2-yl)acetyl]amino]-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoate; PGly-Ile-Trp-OBzl; Fmoc-Protected Tetrapeptide Derivative (related); Peptide Synthesis Intermediate 125009-80-5
EINECS	Contact for details

Quality Control

Our Phthaloyl-Glycyl(P)-Isoleucyl-Tryptophyl-Benzylamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.