Description

4-Methyl-2-(Piperazin-1-Yl)Pyrimidine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in medicinal chemistry. This compound matters for its role as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step production of complex APIs requiring a functionalized pyrimidine-piperazine core structure.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Methyl-2-(Piperazin-1-Yl)Pyrimidine Dihydrochloride
CAS No.	124863-52-1
Molecular Formula	C9H15Cl2N5
Molecular Weight	264.16 g/mol
Synonyms	2-(1-Piperazinyl)-4-methylpyrimidine dihydrochloride; 4-Methyl-2-piperazin-1-ylpyrimidine dihydrochloride; 4-Methyl-2-(1-piperazinyl)pyrimidine dihydrochloride; 4-Methyl-2-(piperazin-1-yl)pyrimidine hydrochloride (1:2); 2-(Piperazin-1-yl)-4-methylpyrimidine dihydrochloride; 4-Methyl-2-piperazinopyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(Piperazin-1-Yl)Pyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.