Description

2-Methyl-6-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a methyl and a trifluoromethyl group on the phenol ring, provides valuable properties such as enhanced lipophilicity and metabolic stability to target molecules. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with improved efficacy and performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Polymer Modification: Employed as a monomer or additive to introduce fluorine into polymer backbones, enhancing chemical resistance, thermal stability, and surface properties of specialty plastics and coatings.
• Organic Electronics: Acts as a building block for electron-transport materials and hole-blocking layers in organic light-emitting diodes (OLEDs) and perovskite solar cells.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways, catalysis, and the synthesis of complex fluorinated aromatic compounds in academic and industrial R&D labs.

Basic Information

Product Name	2-Methyl-6-(Trifluoromethyl)Phenol
CAS No.	124837-37-2
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	2-Hydroxy-3-methylbenzotrifluoride; 3-Methyl-2-(trifluoromethyl)phenol; 2-Methyl-6-trifluoromethylphenol; 6-(Trifluoromethyl)-o-cresol; o-Cresol, 6-(trifluoromethyl)-; 2-Methyl-α,α,α-trifluoro-m-cresol; 2-Methyl-6-(trifluoromethyl)benzenol
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by GC-MS, FT-IR, and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, impurity profiles, and physical characteristics. We support compliance with relevant regulatory frameworks, including REACH and TSCA.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its phenolic nature and light-sensitive properties, prolonged exposure to light or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.