Description

o-4-Propylthymine is a modified nucleobase derivative, specifically a thymine analog with a propyl substituent at the oxygen-4 position. This structural modification makes it a valuable building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and fine chemical manufacturers developing novel nucleoside analogs, antiviral agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a modified base in oligonucleotide synthesis for studying DNA-protein interactions and nucleic acid structure.
• Agrochemical Development: Serves as an intermediate in creating novel pesticides and herbicides with specific modes of action.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Diagnostic Reagent Synthesis: Building block for labeled probes and other diagnostic compounds used in molecular biology.
• Material Science: Potential monomer or modifier in the development of specialized polymers and biomaterials.

Basic Information

Product Name	o-4-Propylthymine
CAS No.	124830-87-1
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	4-Propoxy-2-pyrimidinone; 4-Propoxypyrimidin-2(1H)-one; 2-Hydroxy-4-propoxypyrimidine; 4-Propyloxythymine; O4-Propylthymine; Thymine, O4-propyl-; 1,2-Dihydro-4-propoxy-2-oxopyrimidine
EINECS	Contact for details

Quality Control

Our o-4-Propylthymine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.