Description

1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride is a high-value sulfonyl chloride derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile electrophilic building block, enabling the introduction of the sulfonyl functional group into complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl moiety is essential for bioactivity.
• Functional Material Research: Serves as a building block for creating specialized polymers, dyes, and photoactive materials requiring sulfonyl linkages.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses producing bespoke compounds for client R&D programs.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and sulfonation chemistry.

Basic Information

Product Name	1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride
CAS No.	124788-36-9
Molecular Formula	C6H7ClN2O4S
Molecular Weight	238.65 g/mol
Synonyms	5-(Chlorosulfonyl)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione; 1,3-Dimethyl-5-sulfonylchloridobarbitursäure (German); 1,3-Dimethylbarbituric-5-sulfonyl chloride; 5-Chlorosulfonyl-1,3-dimethylbarbituric acid; NSC 405124; 1,3-Dimethyl-2,4,6-trioxo-5-sulfonylchloridotetrahydropyrimidine; 5-(Chlorosulfonyl)-1,3-dimethyluracil
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.