Description

2-Amino-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile is a high-purity heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of protein kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Development: Building block for creating novel active ingredients with potential herbicidal or fungicidal properties.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying enzyme function and cellular signaling pathways.
• Material Science Research: Serves as a monomer or precursor for specialized organic electronic materials and dyes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clients.
• Academic Research: Utilized in university and institutional labs for methodological development and discovery chemistry projects.

Basic Information

Product Name	2-Amino-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile
CAS No.	124738-81-4
Molecular Formula	C7H4ClN5
Molecular Weight	193.59 g/mol
Synonyms	4-Chloro-2-amino-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile; 2-Amino-4-chloro-5-cyano-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2-amino-5-cyanopyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2-amino-4-chloro-7H-; ACPPC; 124738-81-4; 2-Amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.