Description

S-(2-Aldehydoethyl)Glutathione is a specialized glutathione derivative, a key biochemical tool for research into cellular redox signaling and detoxification pathways. This compound is particularly valuable for studying the interaction of reactive aldehydes with the glutathione system, a critical mechanism in oxidative stress and metabolic regulation. It serves as an essential reference standard and synthetic intermediate for researchers and manufacturers in the fields of pharmaceutical development, biochemical research, and advanced material science.

Application

• Biochemical Research: Critical reference standard and substrate for studying glutathione S-transferase (GST) activity, aldehyde metabolism, and cellular redox balance.
• Pharmaceutical Intermediates: Used in the synthesis of novel drug candidates targeting oxidative stress-related diseases, such as neurodegenerative disorders and inflammatory conditions.
• Metabolite Analysis: Serves as a key analytical standard in LC-MS and HPLC methods for quantifying glutathione-aldehyde adducts in biological samples.
• Enzyme Mechanism Studies: A tool compound for investigating the kinetics and mechanisms of enzymes involved in detoxification pathways.
• Nutritional Science Research: Employed in studies examining the biochemical fate of dietary aldehydes and their interaction with endogenous antioxidants.
• Diagnostic Reagent Development: Potential component in the development of assays and kits for measuring oxidative stress biomarkers.

Basic Information

Product Name	S-(2-Aldehydoethyl)Glutathione
CAS No.	124521-13-7
Molecular Formula	C12H20N3O7S
Molecular Weight	350.37 g/mol
Synonyms	S-(2-Oxoethyl)glutathione; Glutathione, S-(2-oxoethyl)-; 2-(S-Glutathionyl)acetaldehyde; NSC 339587; γ-Glu-Cys-Gly-S-CH2CH=O; S-(2-Aldehydoethyl)-L-glutathione; S-(2-Oxoethyl)-L-glutathione; Glutathione S-(2-oxoethyl) ester
EINECS	Contact for details

Quality Control

Our S-(2-Aldehydoethyl)Glutathione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality system is designed to meet the rigorous demands of pharmaceutical and analytical reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.