Description

Amylin (Mouse, Rat) CAS NO 124447-81-0 is a synthetic 37-amino acid peptide hormone, identical to the endogenous form found in rodents. This high-purity peptide is a critical research tool for studying metabolic regulation, particularly in the context of diabetes and obesity. It is essential for researchers in pharmaceutical development, academic institutions, and contract research organizations (CROs) focused on endocrinology and glucose homeostasis.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating amylin's role in satiety, gastric emptying, and glucagon secretion.
• Diabetes & Obesity Models: Critical for in vitro and in vivo studies using mouse and rat models to understand pathophysiology and evaluate potential therapeutics.
• Receptor Binding Assays: Employed in competitive binding studies to characterize the amylin receptor (AMY) and screen for agonists or antagonists.
• Biochemical Standard: Serves as a quantitative standard in immunoassays (ELISA, RIA) and chromatographic methods (HPLC, LC-MS) for amylin detection.
• Cell Signaling Studies: Applied to cell cultures to study downstream signaling pathways, such as cAMP modulation, activated by amylin receptor engagement.
• Formulation Development: Used in pre-clinical development of amylin analogs or combination therapies for metabolic diseases.

Basic Information

Product Name	Amylin (Mouse, Rat)
CAS No.	124447-81-0
Molecular Formula	C165H263N51O53S2
Molecular Weight	3903.6 g/mol
Synonyms	Islet Amyloid Polypeptide (IAPP), Rodent; Diabetes-Associated Peptide (DAP); Rat Amylin; Mouse Amylin; IAPP (1-37), rat; IAPP (1-37), mouse; Amylin, rat; Amylin, mouse
EINECS	Contact for details

Quality Control

Our Amylin (Mouse, Rat) is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results from multiple orthogonal analytical techniques, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We adhere to GMP principles for research-grade peptides, ensuring traceability, consistency, and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.