Description

Asp-Asp-Asp-Asp-Asp CAS NO 124219-00-7 is a high-purity synthetic pentapeptide composed of five consecutive aspartic acid residues. This compound serves as a critical building block and model substrate in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of peptide synthesis, enzymology, and the study of protein aggregation and neurodegenerative diseases.

Application

• Biochemical Research: Used as a model peptide for studying poly-aspartic acid sequences, protein folding, and aggregation mechanisms relevant to conditions like Alzheimer's disease.
• Enzyme Substrate: Acts as a specific substrate for proteolytic enzymes (e.g., aspartic proteases) in kinetic studies and enzyme characterization assays.
• Pharmaceutical Intermediate: Serves as a key intermediate in the solid-phase or solution-phase synthesis of longer, more complex therapeutic peptides.
• Reference Standard: Employed as a high-purity analytical standard in HPLC and LC-MS methods for peptide quantification and quality control.
• Material Science: Investigated for the development of bio-inspired materials, such as self-assembling peptides and biodegradable polymers, due to its polyanionic character.

Basic Information

Product Name	Asp-Asp-Asp-Asp-Asp
CAS No.	124219-00-7
Molecular Formula	C25H35N5O19
Molecular Weight	733.57 g/mol
Synonyms	L-Aspartyl-L-aspartyl-L-aspartyl-L-aspartyl-L-aspartic acid; Penta-L-aspartic acid; Aspartic acid pentamer; (Asp)5; H-Asp-Asp-Asp-Asp-Asp-OH; Poly(aspartic acid) pentamer; L-Aspartic acid pentapeptide
EINECS	Contact for details

Quality Control

Our Asp-Asp-Asp-Asp-Asp is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.