Description

2,3-Difluoro-6-(trifluoromethyl)aniline is a high-value fluorinated aromatic amine building block. This compound is critical for introducing multiple fluorine atoms into complex molecular architectures, significantly altering the physicochemical properties of target molecules. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique substitution pattern enables fine-tuning of bioactivity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Functional Material Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for heterocyclic compounds in advanced material science.

Basic Information

Product Name	2,3-Difluoro-6-(trifluoromethyl)aniline
CAS No.	124185-34-8
Molecular Formula	C7H4F5N
Molecular Weight	197.11 g/mol
Synonyms	2,3-Difluoro-6-(trifluoromethyl)benzenamine; 2-(Trifluoromethyl)-3,4-difluoroaniline; 3,4-Difluoro-2-(trifluoromethyl)aniline; 2-Amino-3,4-difluorobenzotrifluoride; Benzenamine, 2,3-difluoro-6-(trifluoromethyl)-; 2,3-Difluoro-α,α,α-trifluoro-p-toluidine; 2,3-Difluoro-6-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-(trifluoromethyl)aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfers should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.