Description

8-Bromo-7-Isobutyl-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, functionalized purine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel pharmaceutical intermediates and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential adenosine receptor modulators and other purine-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting neurological and cardiovascular diseases.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new purine-based bioactive compounds.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition, particularly those involving purine metabolism pathways.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to introduce the functionalized purine core into larger molecular architectures.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	8-Bromo-7-Isobutyl-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	123980-54-1
Molecular Formula	C₁₀H₁₃BrN₄O₂
Molecular Weight	301.14 g/mol
Synonyms	8-Bromo-7-isobutyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-7-isobutyl-3-methylxanthine; 8-Bromo-IBMX; 8-Bromo-3-methyl-7-(2-methylpropyl)-1H-purine-2,6-dione; 1H-Purine-2,6-dione, 8-bromo-7-(2-methylpropyl)-3-methyl-; 8-Br-IBMX; 8-Bromo-3-methyl-7-isobutylxanthine; 8-Bromoisobutylmethylxanthine
EINECS	Contact for details

Quality Control

Our 8-Bromo-7-Isobutyl-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.