Description

2-Chloro-6-Fluoro-4-Trifluoromethylaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it a valuable intermediate for creating compounds with enhanced biological activity and specific physical properties. This high-purity intermediate is primarily needed by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by research institutions engaged in materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes.
• Dye & Pigment Manufacturing: Intermediate for creating specialized, high-performance dyes and pigments with improved lightfastness.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce specific properties into polymer chains.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	2-Chloro-6-Fluoro-4-Trifluoromethylaniline
CAS No.	123973-31-9
Molecular Formula	C7H4ClF4N
Molecular Weight	213.56 g/mol
Synonyms	2-Chloro-6-fluoro-4-(trifluoromethyl)aniline; 4-Amino-3-chloro-5-fluorobenzotrifluoride; Benzenamine, 2-chloro-6-fluoro-4-(trifluoromethyl)-; 3-Chloro-5-fluoro-4-aminobenzotrifluoride; 2-Chloro-6-fluoro-alpha,alpha,α-trifluoro-p-toluidine; 2-Chloro-6-fluoro-4-trifluoromethylphenylamine; 4-Trifluoromethyl-2-chloro-6-fluoroaniline; 2-Chloro-6-fluoro-4-trifluoromethyl aniline
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-4-Trifluoromethylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.