Description

2-Fluoro-3-(Trifluoromethyl)Aniline is a high-value fluorinated aromatic amine building block, essential for introducing unique steric and electronic properties into advanced molecular architectures. Its primary commercial value lies in its role as a key intermediate in the synthesis of complex agrochemicals and active pharmaceutical ingredients (APIs). This compound is particularly sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, particularly in kinase inhibitors and CNS-active molecules.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethyl groups confer improved lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing charge transport and stability.
• Polymer & Resin Modifier: Incorporated to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Intermediate: Used in the synthesis of high-performance, light-fast colorants and functional dyes.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to build complex biaryl systems.

Basic Information

Product Name	2-Fluoro-3-(Trifluoromethyl)Aniline
CAS No.	123973-25-1
Molecular Formula	C7H5F4N
Molecular Weight	179.12 g/mol
Synonyms	2-Fluoro-3-(trifluoromethyl)benzenamine; 3-Amino-2-fluorobenzotrifluoride; 2-Fluoro-alpha,alpha,α-trifluoro-m-toluidine; Benzenamine, 2-fluoro-3-(trifluoromethyl)-; 2-Fluoro-3-trifluoromethylaniline; 2-Fluoro-3-(trifluoromethyl)phenylamine; m-Toluidine, 2-fluoro-alpha,alpha,α-trifluoro-; 3-(Trifluoromethyl)-2-fluoroaniline
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.